Illumina Announces BaseSpace Correlation Engine Integration with Elsevier’s Pathway Studio

Accelerates discovery by demonstrating genetic functional relationships and validating results


Illumina and Elsevier R&D Solutions have announced a collaboration to integrate use of Pathway Studio, Elsevier’s database of experimental data and disease models, with Illumina’s BaseSpace Correlation Engine platform, offering them as one seamless solution. Under the terms of the agreement, all licensed Correlation Engine users have free access to Pathway Viewer, an application that enables researchers to quickly view a snapshot of the functional relationships among genes. In addition, researchers are able to find top scoring canonical pathways that correlate most highly with the genes list.

Correlation Engine is a suite of applications that lets users discover the relationships among their results, with billions of correlations derived from the world’s largest curated library of genomic knowledge. The applications contain over 130,000 experimental comparisons from more than a half million samples, drawn from NCBI’s Gene Expression Omnibus and other open-access or controlled-access databases.

“With the quantity of published data increasing on a daily basis, our goal is to ensure that our customers can quickly and easily find authoritative evidence and data that is relevant to their research,” said Jaqui Hodgkinson, VP Product Development, Biology Products, Elsevier. “Our collaboration with Illumina meets this goal by adding more value to our customers by reducing complexity, increasing the accuracy of their analysis and lightening their workloads. Improved accuracy in the early phases of research enables researchers to make confident decisions that support successful outcomes.”

Correlation Engine users are able to access a seamless integration point to transfer and visualize their results with the full functionality of Pathway Studio, thus revealing new insights and assisting with critical decision making. Pathway Studio enables scientists to explore molecular interactions, and cause and effect relationships associated with underlying biological processes.

“Our collaboration extends the reach of the sample to answer solutions provided by Illumina’s BaseSpace Sequence Hub Platform,” said Joe Delaney, Manager of Research Curation at Illumina. “Investigators can now stream their RNA-Seq data directly into SequenceHub for analysis, transport their results for meta-analysis in Correlation Engine, and then visualize and overlay their findings with Elsevier’s repertoire of curated knowledge of genetic relationships.”

For more information on Pathway Studio, please visit:

About Elsevier

Elsevier is a world-leading provider of information solutions that enhance the performance of science, health, and technology professionals, empowering them to make better decisions, deliver better care, and sometimes make groundbreaking discoveries that advance the boundaries of knowledge and human progress. Elsevier provides web-based, digital solutions — among them ScienceDirect, Scopus, Elsevier Research Intelligence and ClinicalKey — and publishes more than 2,500 journals, including The Lancet and Cell, and more than 33,000 book titles, including a number of iconic reference works. Elsevier is part of RELX Group plc, a world-leading provider of information solutions for professional customers across industries.

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